NOW® Glucosamine & MSM with Chondroitin Sulfate combines three well-known joint support ingredients.* Glucosamine is an essential building block for the formation of glycosaminoglycans (GAGs) and proteoglycans, the main components of cartilage tissue.* These compounds promote water retention within the joint, giving it resiliency by acting as a lubricant and a means to absorb shock.* MSM (Methylsulfonylmethane) is an organic form of sulfur, a mineral necessary for the production of GAGs and proteoglycans.*