• Pharmaceutical Grade, Stabilized
• Full Potency
• S-Adenosyl Methionine
• 400 mg (Net Yield) SAM-e from 800 mg SAM-e Tosylate Disulfate
• Highest Concentration of Active S, S Form
• 30 Count
• In Foil Blister Pack
• Vegan
• Gluten Free
• Dietary Supplement

Promotes:

• Longevity
• Joint Strength
• Liver Detoxification
• Mood and Brain Function

Jarrow Formulas SAM-e 400 provides a full 400 mg SAM-e (net yield) from 800 mg of SAM-e tosylate disulfate. SAM-e 400 is manufactured under low temperature and low humidity and is enteric-coated to ensure a biologically active product.
Contains More of the Active S,S Form
Found in all living cells, SAM-e is a metabolite of methionine (an essential amino acid). SAM-e is a chiral molecule and consists of two forms: (S,S) SAM-e and (R,S) SAM-e. The biologically active form is the (S,S) structure, while the (R,S) structure is biologically inactive. Jarrow Formulas SAM-e is made naturally by microbiological fermentation and then specially processed without solvents to preserve 68-80% (S,S) SAM-e, the highest active level available.
SAM-e has been clinically shown to have the following benefits:
Joint Strength
SAM-e supports the production of healthy connective tissues through transulfuration. In this process, critical components of connective tissue, including glucosamine and the chondroitin sulfates, are sulfated by SAM-e metabolites.
Brain Metabolism
SAM-e methylation reactions are involved in the synthesis of neurotransmitters such as L-DOPA, dopamine and related hormones, serotonin, epinephrine and phosphatidylcholine (a component of lecithin).
Longevity
Methylation of DNA appears to be important in the suppression of errors in DNA replication. Demethylation of DNA is considered a contributor to the aging process. Proper methylation through substances such as SAM-e positively influences longevity.
Liver
SAM-e metabolism supports the synthesis of glutathione (GSH) and glutathione – dependent enzymes (glutathione peroxidase and glutathione – S- transferase), which are substances important for liver function.

Take 1 tablet per day on an empty stomach, or as directed by your qualified health care consultant.
For best result, use with Jarrow Formulas JarroSil, the biologically Activated Silicon.

Cellulose, mannitol, glyceryl behenate, magnesium stearate (vegetable source), silicon dioxide, sodium starch, glycolate, enteric coating (methacrylate copolymers), magnesium silicate, titanium dioxide, triethyl citrate, and riboflavin.
Suitable for vegetarians/vegans
No wheat, no gluten, no soybeans, no dairy, no egg, no fish/shellfish, no peanuts/tree nuts
Full Potency 400 mg SAM-e is derived from 800 mg of SAM-e tosylate disulfate.

Individual using prescribed medications such as antidepressants, including Selective Serotonin Re-Uptake Inhibitors (SSRI) and MAO Inhibitors should consult a physician before using. Individuals with Parkinson’s disease, bi-polar disorder or manic depression should not use SAM-e.
This product complies with the proposed USP Monograph for SAM-e.
Jarrow Formulas Sam-e 400 is foil blister-packed to maximize stability and safety. Do not use if outer seal of blister pack is broken.
Store in a cool, dry place.
Keep out of the reach of children.